Advanced Technology, Efficacious Outcomes


The Science of MultiPlexTM




1Geronemus R J Dermatol Surg Oncol. 1993;19:303–310.

2Barton JK, et al. Optical and magnetic resonance changes in photothermally coagulating blood. Proceedings of SPIE 2002; 4609:10-19.

3Kuenstner JT, Norris KH. Spectrophotometry of human hemoglobin in the near infrared region from 1000 to 2500 nm. Near Infrared Spectrosc 1994;2:59-65.



Cynergy Vascular Workstation Specifications


Before & After


I use the [Cynergy Vascular Workstation] in my practice every day. It has quickly become my ‘workhorse’ system for a variety of dermatologic conditions, including facial and leg telangiectasias, port-wine stains, hemangiomas, and hypertrophic scars. I have been so impressed with the versatility of the Cynergy system that I have discontinued the use of a couple of my single-wavelength laser systems.

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Clinical Data

As a recognized industry leader, our technology—including Cynergy technology—is strongly supported by clinical research.

  1. Alster TS, Tanzi EL. Combined 595-nm and 1,064-nm laser irradiation of recalcitrant and hypertrophic port-wine stains in children and adults. Dermatol Surg 2009;35(6):914-8; discussion 918-9. doi: 10.1111/j.1524-4725.2009.01155.x. Epub 2009 Apr 9.
  2. Boixeda, P., et al. Advances in treatment of cutaneous and subcutaneous vascular anomalies by pulsed dual wavelength 595- and 1064-nm application. Medical Laser Application 2008;23:121–126.
  3. González, J.A., et al. Angiolymphoid hyperplasia with eosinophilia treated with vascular laser. Lasers Med Sci 2011;26(3):285-90. doi: 10.1007/s10103-011-0892-3. Epub 2011 Feb 24.
  4. Jung, J.Y.,et al. Comparison of a pulsed dye laser and a combined 585/1,064-nm laser in the treatment of acne vulgaris. Dermatol Surg 2009;35(8):1181-7. doi: 10.1111/j.1524-4725.2008.34427.x. Epub 2009 Jan 21.
  5. Karsai, S., Roos, S., Raulin, C. Treatment of facial telangiectasia using a dual-wavelength laser system (595 and 1,064 nm): a randomized controlled trial with blinded response evaluation. Dermatol Surg 2008;34(5):702-8. doi: 10.1111/j.1524-4725.2008.34131.x. Epub 2008 Mar 3.
  6. Larson, A.A., Goldman, M.P. Recalcitrant rosacea successfully treated with multiplexed pulsed dye laser. J Drugs Dermatol 2007;6(8):843-5.
  7. Li, G., Sun, J., Shao, X., Sang, H., Zhou, Z. The effects of 595- and 1,064-nm lasers on rooster comb blood vessels using dual-wavelength and multipulse techniques. Dermatol Surg 2011;37(10):1473-9. doi: 10.1111/j.1524-4725.2011.02090.x. Epub 2011 Jul 18.
  8. Min, S., et al. Comparison of a long-pulse Nd:YAG laser and a combined 585/1,064-nm laser for the treatment of acne scars: a randomized split-face clinical study. Dermatol Surg 2009;35(11):1720-7. doi: 10.1111/j.1524-4725.2009.01086.x. Epub 2009 Feb 22.
  9. Mordon S, Brisot D, Fournier N. Using a “Non Uniform Pulse Sequence” can improve selective coagulation with a Nd:YAG laser (1.06 microm) thanks to Met-hemoglobin absorption: a clinical study on blue leg veins. Lasers Surg Med 2003;32(2):160-70.
  10. Saafan AM, Salah MM. Using pulsed dual-wavelength 595 and 1064 nm is more effective in the management of hemangiomas. J Drugs Dermatol 2010;9(4):310-4.
  11. Saluja, R. Laser Treatment for Venous Lakes. Review of Ophthalmology. Jobson Medical Information LLC 2011.
  12. Saluja, R. Laser Treatment Aids Rosacea Patients. In: Bernardino, R.C. ed. Review of Opthomology. Aug 2009.
  13. Tanghetti E, Sherr E. Treatment of telangiectasia using the multi-pass technique with the extended pulse width, pulsed dye laser (Cynosure V-Star). J Cosmet Laser Ther 2003;5(2):71-5.
  14. Trelles MA, Weiss R, Moreno-Moragas J, Romero C, Vélez M, Alvarez X. Treatment of leg veins with combined pulsed dye and Nd:YAG lasers: 60 patients assessed at 6 months. Lasers Surg Med 2010;42(9):609-14. doi: 10.1002/lsm.20972.
  15. Tenenbaum, M.J. Cynergy vascular workstation treats rosacea and facila redness with excellent results . Cynosure Whitepaper . 921-0130-000.
  16. Alster, T.S. Cynergy Multiplex Treatment of Port-Wine Stains. Cynosure Whitepaper 2007. 921-5000-000.
  17. Enokibori, M. Treatment of Photoaging in Asian Skin Using Cynergy Pulse Dye (PDL)/Nd:YAG with MultiPlex Feature. Cynosure Whitepaper 2007. 921-1012-000.
  18. Enokibori, M. Pilot Treatment of Vascular Lesions in Asian Skin Types with the Cynergy Pulse Dye (PDL)/Nd:YAG MultiPlex Laser. Cynosure Whitepaper 2007. 921-1011-000.
  19. Neugebauer, D. Treatment of Psoriasis using the 0.45-msec, 585-nm Pulse Dye Laser (PhotoGenica V). Cynosure Whitepaper 2001.
  20. Tanghetti, E. Cynergy with MultiPlex™ Treatment of Telangiectasia. Cynosure Whitepaper 2006. 920-0294-000
  21. Taylor, M.B. MultiPlex 1064/585 nm Laser Treatment of Vascular Lesions. Cynosure Whitepaper 2007. 921-1014-000
  22. Adatto, M. Facial Veins. Cynergy Case Report. 921-0018-000.
  23. Adatto, M. Leg Veins. Cynergy Case Report. 921-0019-000.
  24. Adrian, R. MultiPlex for Leg Veins: Treatment Techniques and Observations. Cynergy Case Report. 921-0387-000
  25. Goldman, M.P., Keel, D.M. Facial Telangiectasia and Facial Rejuvenation. Cynergy Case Report 921-0377-000.
  26. Tanghetti, E. Cynergy with MultiPlex™ Treatment of Telangiectasia. Cynergy Case Report 921-0294-000.
  27. Barton JK, et al. Optical and magnetic resonance changes in photothermally coagulating blood. Proceedings of SPIE 2002; 4609:10-19.
  28. Kuenstner JT, Norris KH. Spectrophotometry of human hemoglobin in the near infrared region from 1000 to 2500 nm. Near Infrared Spectrosc 1994;2:59-65.